Chip and Dale, two chipmunks with noses for trouble, start a detective agency, the Rescue Rangers, along with their new friends Gadget, Monterey Jack, and Zipper. The pint-sized detectives deal with crimes that are often "too small" for the (human) police to handle, usually with other animals as their clients.
The gang frequently finds itself going up against two particular arch-villains: Mafia-style tabby cat Fat Cat, and mad scientist Norton Nimnul. The Rescue Rangers' motto is to watch out for everyone, and whenever anyone is in trouble, they're on the case. This gang would never steal from anybody, has "hearts of gold", and always tries to help others in need.